Abstract:

Aim: was to determine the level of bilateral asymmetry of mineral density of trabecular and cortical bones in lumbar spine in women as an additional diagnostic criterion for osteoporosis, using quantitative computed tomography

Material and methods: the study included 210 women, postmenopausal, who underwent bone densitometry by quantitative computed tomography Estimated total body BMD II-IV of the lumbar vertebrae (separately for trabecular and cortical bone), as well as bilateral asymmetry indices BMD - BMD ratio of the largest one-half of the vertebral BMD to the other half.

Results: with increasing age of the surveyed, noted the growth of bilateral asymmetry index values mineral density of the lumbar vertebrae for both trabecular and cortical bones. Decrease in bone mass of the lumbar vertebrae is associated with an increase in bilateral asymmetry of the BMD. The correlation between the BMD and bilateral asymmetry indices for trabecular bone was r = -0.52 (p=0.001) for cortical bone r = - 0.47 (p=0.001).

Conclusion: the index of bilateral asymmetry in bone mineral density of the vertebral bodies car serve as an additional diagnostic criterion for osteoporosis during bone densitometry by quantitative computed tomography in postmenopausal women.

References

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11.  Zaharov I

Abstract:

Aim: was to compare results of bone densitometry techniques, conducted by quantitative computed tomography (QCT) and dual-energy X-ray absorptiometry (DXA) in postmenopausal women.

Material and methods: the study included 210 women in postmenopausal period, who were divided by age into four groups: 50-59 years, 60-69 years, 70-79 years, 80 years and older. All patients underwent densitometry of the lumbar spine by quantitative computed tomography anc dual-energy X-ray absorptiometry in the range of 1-2 weeks.

Results: in the evaluation of bone mineral density by methods of QCT and DXA in the age group 50-59 years, there were no significant differences in results of densitometry During of QCT, osteoporosis was diagnosed in 20.5%, during DXA - 15.1% of patients. Since the age of 60 years and older - incidence of osteoporosis by QCT was higher than in the DXA. Evaluation of correlation indicators QCT and DXA, in all four groups showed a positive association of moderate strength, which decreases with increasing age (I group: r=0.68, p=0.001; II group: r=0.57, p=0.001; III group: r=0.40, p=0.003; IV group: r=0.40, p=0.04).

Conclusion: after 60 years, the incidence of osteoporosis, shown by quantitative computed tomography is higher in comparison with dual-energy X-ray absorptiometry.